Scrivener??s Palsey not Solely Pen Fatigue

The transcription factor p53: Not a repressor, solely an activator

The predominant function of the tumor suppressor p53 is transcriptional regulation. It is generally accepted that p53-dependent transcriptional activation occurs by binding to a specific recognition site in promoters of target genes. Additionally, several models for p53-dependent transcriptional repression have been postulated. Here, we evaluate these models based on a computational meta-analys...

Leptin-induced weight loss is not solely mediated by anorexia.

The discovery of the ob-gene product leptin in 1994 (1 –2) and the subsequent identification of grossly obese children lacking leptin (3) or its receptor (4) considerably increased the expectation of finding an effective cure for grossly obese humans. Very soon after its discovery it became evident, however, that a deficiency of leptin did not account for obesity in the large majority of patien...

Segmentation of Pen Strokes Using Pen Speed

We present a technique for segmenting pen strokes into lines and arcs. The technique uses pen speed information to help infer the segmentation intended by the drawer. To begin, a set of candidate segment points is identified. This set includes speed minima below a threshold computed from the average pen speed. It also includes curvature maxima at which the pen speed is again below a threshold. ...

del ( 9 q ) solely

+ 10 or trisomy 10 ( solely )

Clinics and pathology Disease ALL or ANLL. Phenotype / cell stem origin ALL cases are mostly pre B ALL; AML cases are M0, M1 or M2 AML, with, in most cases, a CD7+, CD33+ phenotype. Epidemiology Only 6 (poorly described) ALL cases and 9 ANLL cases, herein reviewed; incidence of +10: less than 1% of ANLL; sex ratio in ANLL cases is, so far, 1M/2F, and median age is 60 yrs (37-80 yrs), while ALL ...